Retatrutide is a synthetic peptide developed as a triple receptor agonist targeting the GLP-1, GIP, and glucagon receptors. Its structure is based on a modified peptide backbone with a C20 fatty diacid chain designed to support albumin binding and extended activity. Specific amino-acid modifications provide activity across all three receptor pathways.
Retatrutide has the molecular formula C221H342N46O68, an approximate molecular weight of 4,191.7 g/mol, and CAS No. 2381089-83-2. It is typically supplied as a white to off-white lyophilized powder and is described as soluble in water.
The compound is primarily of interest for laboratory research into metabolic signaling and the combined effects of GLP-1, GIP, and glucagon receptor activity. For research purposes only — not for human or veterinary use.



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